During the last decade cosmetic facial procedures have become part of the professional work of both dentists and maxillofacial surgeons. A shift has taken place from invasive surgical treatment towards minimally invasive treatments. Besides the use of botulinum toxin type A, non-permanent wrinkle fillers can be an alternative to invasive surgical treatment. Since botulism was first described in the 18th century, the neurotoxin has continued to develop, as a result of which Botox, now available in synthetically produced form, can safely be employed in healthcare. The frequency with which patients visit dentists and maxillofacial surgeons offers the professional group the possibility to inform patients about cosmetic facial treatments and to carry them out according to diagnosis.